منابع مشابه
The Effect of Flavonoid Naringenin on Contractile Response of Thoracic Aorta Isolated from Diabetic Rats
Background & Aims: Considering increasing incidence of cardiovascular disorders in diabetes mellitus and some evidence on antioxidant and antidiabetic potentials of naringenin, this study was conducted to evaluate the beneficial effects of 6-week administration of naringenin on contractile reactivity of isolated thoracic aorta in diabetic rats. Methods: Male Wistar rats were divided into contro...
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Vascular aging is associated with structural and functional modifications of the arteries, and by an increase in arterial wall thickening in the intima and the media, mainly resulting from structural modifications of the extracellular matrix (ECM) components. Among the factors known to accumulate with aging, advanced lipid peroxidation end products (ALEs) are a hallmark of oxidative stress-asso...
متن کاملThe Effect of Chlorpyrifos on Isolated Thoracic Aorta in Rats
This study investigated the effect of chlorpyrifos on thoracic aorta and on the level of NO in plasma and aorta. The effect of chlorpyrifos on thoracic aorta in organ bath was determined in 10 rats. Another 45 rats were assigned to 3 groups with 15 rats each: control group 1 received distilled water, control group 2 was given corn oil, and the last group was given 13.5 mg/kg chlorpyrifos dissol...
متن کاملHeartworm extract induces relaxation of isolated rat thoracic aorta
Isolated rat thoracic aortic strips undergoing noradrenaline-induced contraction were treated with an adult heartworm (HW) crude extract and then examined for isometric changes in tension. HW extract caused relaxation of endothelium-intact strips, but not endothelium-denuded strips. This effect was inhibited by treatment with NG-nitro-L-arginine methyl ester hydrochloride (L-NAME) and could be ...
متن کاملThoracic Aorta
Chronic hyperinsulinemia is suspected of enhancing the development of arterial diseases. However, direct metabolic effects of insulin on the inner arterial wall are poorly documented. To assess the possible influence of variations in smooth muscle phenotype, we measured lipogenesis from glucose by rat thoracic aortas that had been injured with a balloon catheter. Aortas were exposed to insulin ...
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ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1975
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.3.2_143